The Buchwald ligand family is now well-known for its use in catalysis

The Buchwald ligand family is now well-known for its use in catalysis

The Buchwald ligand family is now well-known and its use in catalysis has had a significant impact in research and development in the development of C-C and C-N bond forming reactions.

Methanesulfonato(2-dicyclohexylphosphino-2′,6′-di-i-propoxy-1,1′-biphenyl)(2′-amino-1,1′-biphenyl-2-yl)palladium(II), min. 98% [RuPhos Palladacycle Gen. 3] Strem no: 46-0314
CAS: 1445085-77-7

Initially, the use of these ligands was made in conjunction with a palladium precursor leading to the formation of the active species in situ. In order to impart a higher level of control over catalyst formation and delivery into the active catalytic cycle, the area has moved toward the use of well-defined palladium complexes bearing the ligand of choice. This approach has also been taken by the Buchwald group who has developed two components-in-one-complex that brings together the metal center and a series of ligand designed by the MIT group. A palladium complex bearing Ruphos, one of the Buchwald ligands (this one named after Steve’s cat) is available from Strem. This complex has found applications in C-C and C-N bond forming reactions. This item is sold separately and can be found as part of our Buchwald kit.

For further information on this versatile complex and its availability in quantities, please contact us at 01223 873028 or enquiries@www.strem.co.uk